Vitamin D deficiency in pregnancy
Vitamin D physiologically rise in early pregnancy during the first trimester and continue to rise and it is doubling by the end of the third trimester.
There is an accumulating evidence that vitamin D supplementation may be able to prevent immune maladaptation and loss of tolerance that occurs in pre-eclampsia.
Active vitamin D is a potent modulator. It may lead to gestational diabetes and allergic disease. It is essential to prevent vitamin D deficiency in pregnancy. The recommended dose is 10000 units weekly for all pregnant women and 20000 units weekly for pregnant women with vitamin D deficiency.
Role of vitamin D during pregnancy
- Crucial for maternal health and skeletal fetal growth.
- Risk in preventing neonatal hypoxic ischemia, brain injury/ Dose of vitamin D plays a vital role in the neonatal development of the fetus.
- Prevention of pre-eclampsia.
- Prevention of GDM.